Crystallography Open Database
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Result: there are 271 entries in the selection
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Searching journal of publication like 'Journal of medicinal chemistry'
COD ID  |
Links | Formula |
Space group |
Cell parameters | Cell volume  |
Bibliography |
|---|---|---|---|---|---|---|
| 1503670 | CIF | C9 H12 N4 S | P -1 | 7.3747; 7.4532; 9.6324 97.192; 109.63; 95.02 | 489.97 | Kowol, Christian R.; Trondl, Robert; Heffeter, Petra; Arion, Vladimir B.; Jakupec, Michael A.; Roller, Alexander; Galanski, Markus; Berger, Walter; Keppler, Bernhard K. Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation. Journal of medicinal chemistry, 2009, 52, 5032-5043 |
| 1505034 | CIF | C9 H17 N O4 | P 1 21 1 | 7.1718; 6.9079; 10.864 90; 107.338; 90 | 513.77 | Vyavahare, Vinod P.; Chakraborty, Chaitali; Maity, Biswanath; Chattopadhyay, Subrata; Puranik, Vedavati G.; Dhavale, Dilip D. Synthesis of 1-deoxy-1-hydroxymethyl- and 1-deoxy-1-epi-hydroxymethyl castanospermine as new potential immunomodulating agents. Journal of medicinal chemistry, 2007, 50, 5519-5523 |
| 1566550 | CIF | C12 H16 N2 O2 | P -1 | 7.7366; 7.9072; 10.7395 99.872; 102.594; 113.64 | 562.21 | Wittmann, Christopher; Bacher, Felix; Enyedy, Eva A.; Dömötör, Orsolya; Spengler, Gabriella; Madejski, Christian; Reynisson, Jóhannes; Arion, Vladimir B. Highly Antiproliferative Latonduine and Indolo[2,3-<i>c</i>]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile. Journal of medicinal chemistry, 2022, 65, 2238-2261 |
| 1502665 | CIF | C16 H38 Cl2 N6 O2 Pt | P -1 | 7.336; 8.228; 10.622 83.82; 103.76; 103.21 | 605.3 | Marzano, Cristina; Mazzega Sbovata, Silvia; Gandin, Valentina; Colavito, Davide; Del Giudice, Elda; Michelin, Rino A.; Venzo, Alfonso; Seraglia, Roberta; Benetollo, Franco; Schiavon, Mariano; Bertani, Roberta A new class of antitumor trans-amine-amidine-Pt(II) cationic complexes: influence of chemical structure and solvent on in vitro and in vivo tumor cell proliferation. Journal of medicinal chemistry, 2010, 53, 6210-6227 |
| 1505018 | CIF | C9 H11 Cl2 Cu N5 S | P -1 | 8.649; 9.313; 9.371 68.69; 71.86; 79.27 | 666 | Tardito, Saverio; Bussolati, Ovidio; Maffini, Monica; Tegoni, Matteo; Giannetto, Marco; Dall'asta, Valeria; Franchi-Gazzola, Renata; Lanfranchi, Maurizio; Pellinghelli, Maria Angela; Mucchino, Claudio; Mori, Giovanni; Marchio, Luciano Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells. Journal of medicinal chemistry, 2007, 50, 1916-1924 |
| 1505032 | CIF | C30 H48 N2 O3 | P 1 | 6.135; 6.77; 17.17 92.3; 97.87; 99.35 | 695.6 | Sauvaître, Thibault; Barlier, Mireille; Herlem, Denyse; Gresh, Nohad; Chiaroni, Angèle; Guenard, Daniel; Guillou, Catherine New potent acetylcholinesterase inhibitors in the tetracyclic triterpene series. Journal of medicinal chemistry, 2007, 50, 5311-5323 |
| 1508520 | CIF | C7 H17 Cl2 F3 N2 O4 Pt | P -1 | 6.1836; 8.0658; 15.5374 102.217; 92.75; 108.655 | 711.98 | Pichler, Verena; Heffeter, Petra; Valiahdi, Seied M.; Kowol, Christian R.; Egger, Alexander; Berger, Walter; Jakupec, Michael A.; Galanski, Markus; Keppler, Bernhard K. Unsymmetric Mono- and Dinuclear Platinum(IV) Complexes Featuring an Ethylene Glycol Moiety: Synthesis, Characterization, and Biological Activity. Journal of medicinal chemistry, 2012, 55, 11052-11061 |
| 1552489 | CIF | C26 H30 F3 N7 O9 | P 1 | 5.0591; 10.9615; 13.2 103.037; 90.846; 90.3108 | 713.03 | Policarpo, Rocco L.; Decultot, Ludovic; May, Elizabeth; Kuzmič, Petr; Carlson, Samuel; Huang, Danny; Chu, Vincent; Wright, Brandon A.; Dhakshinamoorthy, Saravanakumar; Kannt, Aimo; Rani, Shilpa; Dittakavi, Sreekanth; Panarese, Joseph D.; Gaudet, Rachelle; Shair, Matthew D. High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide <i>N</i>-Methyltransferase (NNMT). Journal of medicinal chemistry, 2019 |
| 1561876 | CIF | C13 H11 Cl Cu N4 S2 | P -1 | 8.6462; 9.7989; 10.1011 68.887; 71.065; 82.137 | 755 | Gou, Yi; Chen, MeiRong; Li, Shanhe; Deng, JunGang; Li, Jinlong; Fang, GuiHua; Yang, Feng; Huang, GuoJin Dithiocarbazate-Copper Complexes for Bioimaging and Treatment of Pancreatic Cancer. Journal of medicinal chemistry, 2021 |
| 1503664 | CIF | C17 H26 N2 O2 | P 1 21 1 | 6.6457; 10.369; 11.3174 90; 92.645; 90 | 779.04 | Fox, David J.; Reckless, Jill; Lingard, Hannah; Warren, Stuart; Grainger, David J. Highly potent, orally available anti-inflammatory broad-spectrum chemokine inhibitors. Journal of medicinal chemistry, 2009, 52, 3591-3595 |
| 1502659 | CIF | C17 H18 N4 O2 S | P -1 | 8.187; 10.274; 11.169 116.031; 92.445; 108.955 | 779.2 | Ivachtchenko, Alexandre V.; Dmitriev, Dmitri E.; Golovina, Elena S.; Kadieva, Madina G.; Koryakova, Angela G.; Kysil, Volodymyr M.; Mitkin, Oleg D.; Okun, Ilya M.; Tkachenko, Sergey E.; Vorobiev, Anton A. (3-Phenylsulfonylcycloalkano[e and d]pyrazolo[1,5-a]pyrimidin-2-yl)amines: potent and selective antagonists of the serotonin 5-HT6 receptor. Journal of medicinal chemistry, 2010, 53, 5186-5196 |
| 1561877 | CIF | C26 H22 Cu2 N10 O6 S4 | P -1 | 7.9731; 9.8264; 10.9176 76.501; 85.908; 73.399 | 797.05 | Gou, Yi; Chen, MeiRong; Li, Shanhe; Deng, JunGang; Li, Jinlong; Fang, GuiHua; Yang, Feng; Huang, GuoJin Dithiocarbazate-Copper Complexes for Bioimaging and Treatment of Pancreatic Cancer. Journal of medicinal chemistry, 2021 |
| 1529317 | CIF | C16 H14 I N5 | P 1 21 1 | 8.499; 8.394; 11.73 90; 104.19; 90 | 811.292 | Scheuermann, Thomas H.; Stroud, Daniel; Sleet, Christopher E.; Bayeh, Liela; Shokri, Cameron; Wang, Hanzhi; Caldwell, Charles G.; Longgood, Jamie; MacMillan, John B.; Bruick, Richard K.; Gardner, Kevin H.; Tambar, Uttam K. Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2. Journal of medicinal chemistry, 2015, 58, 5930-5941 |
| 1566546 | CIF | C32 H39 Cl3 Cu N8 O3 | P 1 | 7.2313; 9.2604; 14.1201 78.16; 77.214; 70.423 | 859.9 | Wittmann, Christopher; Bacher, Felix; Enyedy, Eva A.; Dömötör, Orsolya; Spengler, Gabriella; Madejski, Christian; Reynisson, Jóhannes; Arion, Vladimir B. Highly Antiproliferative Latonduine and Indolo[2,3-<i>c</i>]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile. Journal of medicinal chemistry, 2022, 65, 2238-2261 |
| 1553267 | CIF | C12 H22 Cl Cu N5 O4 S | P -1 | 9.2626; 9.5087; 11.0617 89.565; 76.519; 67.742 | 873.29 | Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of medicinal chemistry, 2019, 62, 512-530 |
| 1505035 | CIF | C10 H4 O2 S2 | P 1 21/c 1 | 8.96; 14.8156; 6.7569 90; 102.962; 90 | 874.11 | Hyatt, Janice L.; Wadkins, Randy M.; Tsurkan, Lyudmila; Hicks, Latorya D.; Hatfield, M. Jason; Edwards, Carol C.; Ross, 2nd, Charles R; Cantalupo, Stephanie A.; Crundwell, Guy; Danks, Mary K.; Guy, R. Kip; Potter, Philip M. Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1. Journal of medicinal chemistry, 2007, 50, 5727-5734 |
| 1553279 | CIF | C9 H7 Cl N4 | P 1 21/n 1 | 8.2465; 6.6263; 16.392 90; 97.969; 90 | 887.07 | Tokarenko, Anna; Lišková, Barbora; Smoleń, Sabina; Táborská, Natálie; Tichý, Michal; Gurská, Soňa; Perlíková, Pavla; Frydrych, Ivo; Tloušt'ová, Eva; Znojek, Pawel; Mertlíková-Kaiserová, Helena; Poštová Slavětínská, Lenka; Pohl, Radek; Klepetářová, Blanka; Khalid, Noor-Ul-Ain; Wenren, Yiqian; Laposa, Rebecca R.; Džubák, Petr; Hajdúch, Marián; Hocek, Michal Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides. Journal of medicinal chemistry, 2018, 61, 9347-9359 |
| 1508820 | CIF | C12 H22 Cl2 N2 O8 Pt | P -1 | 8.2185; 10.0375; 12.4165 67.002; 71.136; 84.577 | 891.63 | Varbanov, Hristo P.; Jakupec, Michael A.; Roller, Alexander; Jensen, Frank; Galanski, Markus; Keppler, Bernhard K. Theoretical Investigations and Density Functional Theory Based Quantitative Structure-Activity Relationships Model for Novel Cytotoxic Platinum(IV) Complexes. Journal of medicinal chemistry, 2013, 56, 330-344 |
| 1542365 | CIF | C22 H17 F O3 S | P -1 | 5.7185; 11.8378; 13.7061 79.111; 86.121; 80.29 | 897.45 | Xiong, Rui; Patel, Hitisha K.; Gutgesell, Lauren M.; Zhao, Jiong; Delgado-Rivera, Loruhama; Pham, Thao N. D.; Zhao, Huiping; Carlson, Kathryn; Martin, Teresa; Katzenellenbogen, John A.; Moore, Terry W.; Tonetti, Debra A.; Thatcher, Gregory R. J. Selective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer. Journal of medicinal chemistry, 2016, 59, 219-237 |
| 1502674 | CIF | C19 H28 N4 O3 | P -1 | 7.3381; 10.1087; 13.655 74.375; 75.612; 70.157 | 903.66 | Vernekar, Sanjeev Kumar V.; Hallaq, Hasan Y.; Clarkson, Guy; Thompson, Andrew J.; Silvestri, Linda; Lummis, Sarah C. R.; Lochner, Martin Toward biophysical probes for the 5-HT3 receptor: structure-activity relationship study of granisetron derivatives. Journal of medicinal chemistry, 2010, 53, 2324-2328 |
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