Crystallography Open Database
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Searching journal of publication like 'Journal of Medicinal Chemistry'
COD ID  |
Links | Formula  |
Space group |
Cell parameters | Cell volume |
Bibliography |
|---|---|---|---|---|---|---|
| 1552562 | CIF | C10 H12 F2 N2 O5 | P 21 21 21 | 5.8735; 13.5166; 14.1374 90; 90; 90 | 1122.36 | Yoon, Ji-Seong; Kim, Gyudong; Jarhad, Dnyandev B.; Kim, Hong-Rae; Shin, Young-Sup; Qu, Shuhao; Sahu, Pramod K.; Kim, Hea Ok; Lee, Hyuk Woo; Wang, Su Bin; Kong, Yun Jeong; Chang, Tong-Shin; Ogando, Natacha S.; Kovacikova, Kristina; Snijder, Eric J.; Posthuma, Clara C.; van Hemert, Martijn J.; Jeong, Lak Shin Design, Synthesis, and Anti-RNA Virus Activity of 6'-Fluorinated-Aristeromycin Analogues. Journal of medicinal chemistry, 2019, 62, 6346-6362 |
| 1507789 | CIF | C10 H12 F3 N3 O5 Pt | P 1 21/c 1 | 18.336; 7.1871; 10.8106 90; 100.556; 90 | 1400.5 | Wilson, Justin J.; Lippard, Stephen J. In Vitro Anticancer Activity of cis-Diammineplatinum(II) Complexes with β-Diketonate Leaving Group Ligands. Journal of medicinal chemistry, 2012, 55, 5326-5336 |
| 1552560 | CIF | C10 H13 F N2 O5 | P 32 2 1 | 6.6465; 6.6465; 43.3632 90; 90; 120 | 1658.97 | Yoon, Ji-Seong; Kim, Gyudong; Jarhad, Dnyandev B.; Kim, Hong-Rae; Shin, Young-Sup; Qu, Shuhao; Sahu, Pramod K.; Kim, Hea Ok; Lee, Hyuk Woo; Wang, Su Bin; Kong, Yun Jeong; Chang, Tong-Shin; Ogando, Natacha S.; Kovacikova, Kristina; Snijder, Eric J.; Posthuma, Clara C.; van Hemert, Martijn J.; Jeong, Lak Shin Design, Synthesis, and Anti-RNA Virus Activity of 6'-Fluorinated-Aristeromycin Analogues. Journal of medicinal chemistry, 2019, 62, 6346-6362 |
| 5000285 | CIF | C10 H15 Br2 Cl3 | P 21 21 21 | 6.115; 12.456; 19.188 90; 90; 90 | 1461.52 | Fuller, Richard W.; Cardellina, John H.; Kato, Yoko; Brinen, Linda S.; Clardy, Jon; Snader, Kenneth M.; Boyd, Michael R. A pentahalogenated monoterpene from the red alga Portieria hornemannii produces a novel cytotoxicity profile against a diverse panel of human tumor cell lines Journal of Medicinal Chemistry, 1992, 35, 3007-3011 |
| 1507788 | CIF | C10 H15 N3 O5 Pt | P c a 21 | 9.4898; 15.218; 8.9436 90; 90; 90 | 1291.6 | Wilson, Justin J.; Lippard, Stephen J. In Vitro Anticancer Activity of cis-Diammineplatinum(II) Complexes with β-Diketonate Leaving Group Ligands. Journal of medicinal chemistry, 2012, 55, 5326-5336 |
| 1516003 | CIF | C10 H17 N5 O6 | P 21 21 21 | 7.1785; 10.0813; 17.096 90; 90; 90 | 1237.2 | Clinch, Keith; Watt, Derek K.; Dixon, Rachel A.; Baars, Sylvia M.; Gainsford, Graeme J.; Tiwari, Ashish; Schwarz, Günter; Saotome, Yas; Storek, Michael; Belaidi, Abdel A.; Santamaria-Araujo, Jose A Synthesis of cyclic pyranopterin monophosphate, a biosynthetic intermediate in the molybdenum cofactor pathway. Journal of medicinal chemistry, 2013, 56, 1730-1738 |
| 1505035 | CIF | C10 H4 O2 S2 | P 1 21/c 1 | 8.96; 14.8156; 6.7569 90; 102.962; 90 | 874.11 | Hyatt, Janice L.; Wadkins, Randy M.; Tsurkan, Lyudmila; Hicks, Latorya D.; Hatfield, M. Jason; Edwards, Carol C.; Ross, 2nd, Charles R; Cantalupo, Stephanie A.; Crundwell, Guy; Danks, Mary K.; Guy, R. Kip; Potter, Philip M. Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1. Journal of medicinal chemistry, 2007, 50, 5727-5734 |
| 1508515 | CIF | C10.5 H17 Cl2 N2 O4.5 Pt | P 1 21/c 1 | 13.66; 9.867; 23.937 90; 98.52; 90 | 3190.7 | Chin, Chee Fei; Tian, Quan; Setyawati, Magdiel Inggrid; Fang, Wanru; Tan, Emelyn Sue Qing; Leong, David Tai; Ang, Wee Han Tuning the activity of platinum(IV) anticancer complexes through asymmetric acylation. Journal of medicinal chemistry, 2012, 55, 7571-7582 |
| 1552561 | CIF | C11 H16 F2 N5 O4.5 | P 1 21 1 | 10.20373; 6.97368; 18.69692 90; 96.8278; 90 | 1320.99 | Yoon, Ji-Seong; Kim, Gyudong; Jarhad, Dnyandev B.; Kim, Hong-Rae; Shin, Young-Sup; Qu, Shuhao; Sahu, Pramod K.; Kim, Hea Ok; Lee, Hyuk Woo; Wang, Su Bin; Kong, Yun Jeong; Chang, Tong-Shin; Ogando, Natacha S.; Kovacikova, Kristina; Snijder, Eric J.; Posthuma, Clara C.; van Hemert, Martijn J.; Jeong, Lak Shin Design, Synthesis, and Anti-RNA Virus Activity of 6'-Fluorinated-Aristeromycin Analogues. Journal of medicinal chemistry, 2019, 62, 6346-6362 |
| 1518628 | CIF | C11 H17 Cl F N O Pt S | P 1 21/c 1 | 5.9315; 12.1005; 19.7 90; 103.067; 90 | 1377.34 | Zamora, Ana; Pérez, Sergio A; Rodríguez, Venancio; Janiak, Christoph; Yellol, Gorakh S.; Ruiz, José Dual Antitumor and Antiangiogenic Activity of Organoplatinum(II) Complexes. Journal of medicinal chemistry, 2015, 58, 1320-1336 |
| 1503666 | CIF | C11 H20 N2 O2 | P 1 21 1 | 11.4279; 9.9784; 16.245 90; 93.967; 90 | 1848.01 | Fox, David J.; Reckless, Jill; Lingard, Hannah; Warren, Stuart; Grainger, David J. Highly potent, orally available anti-inflammatory broad-spectrum chemokine inhibitors. Journal of medicinal chemistry, 2009, 52, 3591-3595 |
| 1553255 | CIF | C12 H11 N O3 | P 21 21 21 | 6.917; 8.4769; 18.1729 90; 90; 90 | 1065.56 | Xue, Yu; Song, Peiran; Song, Zilan; Wang, Aoli; Tong, Linjiang; Geng, Meiyu; Ding, Jian; Liu, Qingsong; Sun, Liping; Xie, Hua; Zhang, Ao Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrimido[5,4- b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors. Journal of medicinal chemistry, 2018, 61, 4608-4627 |
| 1507499 | CIF | C12 H13 Br Cl N3 S | P 1 21/c 1 | 21.335; 9.315; 14.491 90; 102.995; 90 | 2806.12 | Schröder, Jörg; Henke, Andreas; Wenzel, Herbert; Brandstetter, Hans; Stammler, Hans G.; Stammler, Anja; Pfeiffer, Wolf D.; Tschesche, Harald Structure-Based Design and Synthesis of Potent Matrix Metalloproteinase Inhibitors Derived from a 6H-1,3,4-Thiadiazine Scaffold Journal of Medicinal Chemistry, 2001, 44, 3231 |
| 1519611 | CIF | C12 H15 F N6 O4 | P 43 | 7.3545; 7.3545; 27.835 90; 90; 90 | 1505.6 | Yang, Qinghua; Kang, Jinfeng; Zheng, Liyun; Wang, Xue-Jun; Wan, Na; Wu, Jie; Qiao, Yan; Niu, Pengfei; Wang, Sheng-Qi; Peng, Youmei; Wang, Qingduan; Yu, Wenquan; Chang, Junbiao Synthesis and biological evaluation of 4-substituted fluoronucleoside analogs for the treatment of hepatitis B virus infection. Journal of medicinal chemistry, 2015, 58, 3693-3703 |
| 1503455 | CIF | C12 H16 Br N3 O2 S | P 1 21/c 1 | 10.18411; 14.96067; 9.13052 90; 99.2862; 90 | 1372.9 | Baud, Matthias G. J.; Leiser, Thomas; Haus, Patricia; Samlal, Sharon; Wong, Ai Ching; Wood, Robert J.; Petrucci, Vanessa; Gunaratnam, Mekala; Hughes, Siobhan M.; Buluwela, Lakjaya; Turlais, Fabrice; Neidle, Stephen; Meyer-Almes, Franz-Josef; White, Andrew J. P.; Fuchter, Matthew J. Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets. Journal of medicinal chemistry, 2012, 55, 1731-1750 |
| 1566550 | CIF | C12 H16 N2 O2 | P -1 | 7.7366; 7.9072; 10.7395 99.872; 102.594; 113.64 | 562.21 | Wittmann, Christopher; Bacher, Felix; Enyedy, Eva A.; Dömötör, Orsolya; Spengler, Gabriella; Madejski, Christian; Reynisson, Jóhannes; Arion, Vladimir B. Highly Antiproliferative Latonduine and Indolo[2,3-<i>c</i>]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile. Journal of medicinal chemistry, 2022, 65, 2238-2261 |
| 1553271 | CIF | C12 H17 N5 O S | P 1 21/c 1 | 11.544; 13.204; 10.086 90; 112.081; 90 | 1424.6 | Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of medicinal chemistry, 2019, 62, 512-530 |
| 1559415 | CIF | C12 H18 O2 Si | P 1 21/c 1 | 14.814; 7.972; 10.798 90; 100.7; 90 | 1253 | Kleemiss, Florian; Justies, Aileen; Duvinage, Daniel; Watermann, Patrick; Ehrke, Eric; Sugimoto, Kunihisa; Fugel, Malte; Malaspina, Lorraine A.; Dittmer, Anneke; Kleemiss, Torsten; Puylaert, Pim; King, Nelly R.; Staubitz, Anne; Tzschentke, Thomas M.; Dringen, Ralf; Grabowsky, Simon; Beckmann, Jens Sila-Ibuprofen. Journal of medicinal chemistry, 2020 |
| 1553267 | CIF | C12 H22 Cl Cu N5 O4 S | P -1 | 9.2626; 9.5087; 11.0617 89.565; 76.519; 67.742 | 873.29 | Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of medicinal chemistry, 2019, 62, 512-530 |
| 1508820 | CIF | C12 H22 Cl2 N2 O8 Pt | P -1 | 8.2185; 10.0375; 12.4165 67.002; 71.136; 84.577 | 891.63 | Varbanov, Hristo P.; Jakupec, Michael A.; Roller, Alexander; Jensen, Frank; Galanski, Markus; Keppler, Bernhard K. Theoretical Investigations and Density Functional Theory Based Quantitative Structure-Activity Relationships Model for Novel Cytotoxic Platinum(IV) Complexes. Journal of medicinal chemistry, 2013, 56, 330-344 |
| 1505036 | CIF | C12 H26 Cl2 N2 O9 Pt | P n a 21 | 23.5231; 10.6395; 8.1822 90; 90; 90 | 2047.79 | Reithofer, Michael R.; Valiahdi, Seied M.; Jakupec, Michael A.; Arion, Vladimir B.; Egger, Alexander; Galanski, Markus; Keppler, Bernhard K. Novel di- and tetracarboxylatoplatinum(IV) complexes. Synthesis, characterization, cytotoxic activity, and DNA platination. Journal of medicinal chemistry, 2007, 50, 6692-6699 |
| 1561876 | CIF | C13 H11 Cl Cu N4 S2 | P -1 | 8.6462; 9.7989; 10.1011 68.887; 71.065; 82.137 | 755 | Gou, Yi; Chen, MeiRong; Li, Shanhe; Deng, JunGang; Li, Jinlong; Fang, GuiHua; Yang, Feng; Huang, GuoJin Dithiocarbazate-Copper Complexes for Bioimaging and Treatment of Pancreatic Cancer. Journal of medicinal chemistry, 2021 |
| 1507655 | CIF | C13 H15 Fe N O Se | C 1 2/c 1 | 17.983; 7.4102; 19.235 90; 93.649; 90 | 2558 | Gutiérrez-Hernández, Alejandro I; López-Cortés, José G; Ortega-Alfaro, M Carmen; Ramírez-Apan, M Teresa; Cázares-Marinero, José de Jesús; Toscano, Rubén A Ferrocenylselenoamides: synthesis, characterization and cytotoxic properties. Journal of medicinal chemistry, 2012, 55, 4652-4663 |
| 1557184 | CIF | C13 H15 N3 O5 | P 21 21 21 | 8.4194; 8.5433; 19.1641 90; 90; 90 | 1378.46 | Yang, Yaxi; Zhang, Rukang; Li, Zhaojun; Mei, Lianghe; Wan, Shili; Ding, Hong; Chen, Zhifeng; Xing, Jing; Feng, Huijin; Han, Jie; Jiang, Hualiang; Zheng, Mingyue; Luo, Cheng; Zhou, Bing Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors. Journal of medicinal chemistry, 2020 |
| 1552488 | CIF | C13 H15 N3 O5 S | P 1 21/c 1 | 12.3726; 11.22; 10.9487 90; 99.0665; 90 | 1500.92 | Shao, Xuwei; AbdelKhalek, Ahmed; Abutaleb, Nader S.; Velagapudi, Uday Kiran; Yoganathan, Sabesan; Seleem, Mohamed N.; Talele, Tanaji T. Chemical Space Exploration around Thieno[3,2-<i>d</i>]pyrimidin-4(3<i>H</i>)-one Scaffold Led to a Novel Class of Highly Active <i>Clostridium difficile</i> Inhibitors. Journal of medicinal chemistry, 2019 |
| 1553269 | CIF | C13 H18 Cl Cu N5 O S | C 1 2/c 1 | 15.7566; 14.2967; 14.2703 90; 92.971; 90 | 3210.3 | Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of medicinal chemistry, 2019, 62, 512-530 |
| 1559416 | CIF | C13 H18 O2 | P 1 21/c 1 | 14.465; 7.815; 10.435 90; 99.66; 90 | 1162.9 | Kleemiss, Florian; Justies, Aileen; Duvinage, Daniel; Watermann, Patrick; Ehrke, Eric; Sugimoto, Kunihisa; Fugel, Malte; Malaspina, Lorraine A.; Dittmer, Anneke; Kleemiss, Torsten; Puylaert, Pim; King, Nelly R.; Staubitz, Anne; Tzschentke, Thomas M.; Dringen, Ralf; Grabowsky, Simon; Beckmann, Jens Sila-Ibuprofen. Journal of medicinal chemistry, 2020 |
| 1552490 | CIF | C13 H18 O4 | P 1 21 1 | 5.7618; 19.4824; 11.8204 90; 90.0232; 90 | 1326.88 | Policarpo, Rocco L.; Decultot, Ludovic; May, Elizabeth; Kuzmič, Petr; Carlson, Samuel; Huang, Danny; Chu, Vincent; Wright, Brandon A.; Dhakshinamoorthy, Saravanakumar; Kannt, Aimo; Rani, Shilpa; Dittakavi, Sreekanth; Panarese, Joseph D.; Gaudet, Rachelle; Shair, Matthew D. High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide <i>N</i>-Methyltransferase (NNMT). Journal of medicinal chemistry, 2019 |
| 1553275 | CIF | C13 H19 N5 O S | P 1 21/c 1 | 22.7776; 6.8585; 9.88 90; 98.889; 90 | 1524.92 | Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of medicinal chemistry, 2019, 62, 512-530 |
| 1518236 | CIF | C13 H27 N O4 S | P 1 21 1 | 6.0994; 22.475; 11.962 90; 91.895; 90 | 1638.9 | Maolanon, Alex R.; Villadsen, Jesper S.; Christensen, Niels J.; Hoeck, Casper; Friis, Tina; Harris, Pernille; Gotfredsen, Charlotte H.; Fristrup, Peter; Olsen, Christian A. Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles. Journal of medicinal chemistry, 2014, 57, 9644-9657 |
| 1505041 | CIF | C130 H133 Br4 Cl8 N16 O3.5 Os4 | P -1 | 13.8319; 14.1376; 18.3912 98.511; 107.338; 102.012 | 3271.8 | Schmid, Wolfgang F.; John, Roland O.; Mühlgassner, Gerhard; Heffeter, Petra; Jakupec, Michael A.; Galanski, Markus; Berger, Walter; Arion, Vladimir B.; Keppler, Bernhard K. Metal-based paullones as putative CDK inhibitors for antitumor chemotherapy. Journal of medicinal chemistry, 2007, 50, 6343-6355 |
| 1516882 | CIF | C14 H13 I O2 | P b c a | 7.8201; 15.7081; 21.1791 90; 90; 90 | 2601.6 | Yang, Yanping; Cui, Mengchao; Zhang, Xiaoyang; Dai, Jiapei; Zhang, Zhiyong; Lin, Chunping; Guo, Yuzhi; Liu, Boli Radioiodinated Benzyloxybenzene Derivatives: A Class of Flexible Ligands Target to β-Amyloid Plaques in Alzheimer's Brains. Journal of medicinal chemistry, 2014, 57, 6030-6042 |
| 1516883 | CIF | C14 H13 I O2 | P n a 21 | 6.1079; 7.2239; 28.327 90; 90; 90 | 1249.9 | Yang, Yanping; Cui, Mengchao; Zhang, Xiaoyang; Dai, Jiapei; Zhang, Zhiyong; Lin, Chunping; Guo, Yuzhi; Liu, Boli Radioiodinated Benzyloxybenzene Derivatives: A Class of Flexible Ligands Target to β-Amyloid Plaques in Alzheimer's Brains. Journal of medicinal chemistry, 2014, 57, 6030-6042 |
| 1503662 | CIF | C14 H13 N O3 S2 | P c a 21 | 13.516; 9.108; 22.558 90; 90; 90 | 2777 | Agrawal, Arpita; de Oliveira, César Augusto F; Cheng, Yuhui; Jacobsen, Jennifer A.; McCammon, J. Andrew; Cohen, Seth M. Thioamide hydroxypyrothiones supersede amide hydroxypyrothiones in potency against anthrax lethal factor. Journal of medicinal chemistry, 2009, 52, 1063-1074 |
| 1505016 | CIF | C14 H14 Cl4 Cu2 N10 | P 1 21/a 1 | 8.346; 14.28; 8.376 90; 93.43; 90 | 996.5 | Tardito, Saverio; Bussolati, Ovidio; Maffini, Monica; Tegoni, Matteo; Giannetto, Marco; Dall'asta, Valeria; Franchi-Gazzola, Renata; Lanfranchi, Maurizio; Pellinghelli, Maria Angela; Mucchino, Claudio; Mori, Giovanni; Marchio, Luciano Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells. Journal of medicinal chemistry, 2007, 50, 1916-1924 |
| 1506349 | CIF | C14 H16 Cu Fe N10 O5 S | P 1 21/n 1 | 13.157; 13.641; 14.205 90; 115.98; 90 | 2291.8 | Belicchi-Ferrari, Marisa; Bisceglie, Franco; Casoli, Claudio; Durot, Stéphanie; Morgenstern-Badarau, Irène; Pelosi, Giorgio; Pilotti, Elisabetta; Pinelli, Silvana; Tarasconi, Pieralberto Copper(II) and cobalt(III) pyridoxal thiosemicarbazone complexes with nitroprusside as counterion: syntheses, electronic properties, and antileukemic activity. Journal of medicinal chemistry, 2005, 48, 1671-1675 |
| 1505019 | CIF | C14 H19.5 Cl2 N Na O6.75 | P 1 21 1 | 9.554; 39.491; 9.8412 90; 90.729; 90 | 3712.75 | Llinàs, Antonio; Burley, Jonathan C.; Box, Karl J.; Glen, Robert C.; Goodman, Jonathan M. Diclofenac solubility: independent determination of the intrinsic solubility of three crystal forms. Journal of medicinal chemistry, 2007, 50, 979-983 |
| 1553274 | CIF | C14 H21 N5 O S | P 1 21/c 1 | 6.1236; 7.95; 30.956 90; 92.419; 90 | 1505.68 | Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of medicinal chemistry, 2019, 62, 512-530 |
| 1552491 | CIF | C14 H22 O5 | P 21 21 21 | 5.7488; 9.3963; 27.2172 90; 90; 90 | 1470.2 | Policarpo, Rocco L.; Decultot, Ludovic; May, Elizabeth; Kuzmič, Petr; Carlson, Samuel; Huang, Danny; Chu, Vincent; Wright, Brandon A.; Dhakshinamoorthy, Saravanakumar; Kannt, Aimo; Rani, Shilpa; Dittakavi, Sreekanth; Panarese, Joseph D.; Gaudet, Rachelle; Shair, Matthew D. High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide <i>N</i>-Methyltransferase (NNMT). Journal of medicinal chemistry, 2019 |
| 1508918 | CIF | C14 H24 Cu N6 S2 | P -1 | 7.58; 12.83; 18.298 98.489; 99.605; 91.102 | 1733.6 | Palanimuthu, Duraippandi; Shinde, Sridevi Vijay; Somasundaram, Kumaravel; Samuelson, Ashoka G. In Vitro and in Vivo Anticancer Activity of Copper Bis(thiosemicarbazone) Complexes. Journal of medicinal chemistry, 2013, 56, 722-734 |
| 1503665 | CIF | C14 H24 N2 O2 | P 21 21 21 | 10.2116; 10.8607; 13.1256 90; 90; 90 | 1455.7 | Fox, David J.; Reckless, Jill; Lingard, Hannah; Warren, Stuart; Grainger, David J. Highly potent, orally available anti-inflammatory broad-spectrum chemokine inhibitors. Journal of medicinal chemistry, 2009, 52, 3591-3595 |
| 1557186 | CIF | C15 H14 N4 O2 | P 21 21 21 | 5.8178; 16.9835; 28.2863 90; 90; 90 | 2794.9 | Yang, Yaxi; Zhang, Rukang; Li, Zhaojun; Mei, Lianghe; Wan, Shili; Ding, Hong; Chen, Zhifeng; Xing, Jing; Feng, Huijin; Han, Jie; Jiang, Hualiang; Zheng, Mingyue; Luo, Cheng; Zhou, Bing Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors. Journal of medicinal chemistry, 2020 |
| 1566736 | CIF | C15 H14 O3 | P 21 21 21 | 5.5437; 8.4551; 52.42 90; 90; 90 | 2457.06 | Müller, Christoph; Gleixner, Jakob; Tahk, Maris-Johanna; Kopanchuk, Sergei; Laasfeld, Tõnis; Weinhart, Michael; Schollmeyer, Dieter; Betschart, Martin U.; Lüdeke, Steffen; Koch, Pierre; Rinken, Ago; Keller, Max Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y<sub>1</sub> Receptor. Journal of medicinal chemistry, 2022, 65, 4832-4853 |
| 1529429 | CIF | C15 H17 F3 O3 | P 21 21 21 | 8.511; 11.945; 14.173 90; 90; 90 | 1440.9 | Yang, Zhong-Jin; Ge, Wei-Zhi; Li, Qiu-Ying; Lu, Yaxin; Gong, Jian-Miao; Kuang, Bei-Jia; Xi, Xiaonan; Wu, Haiting; Zhang, Quan; Chen, Yue Syntheses and Biological Evaluation of Costunolide, Parthenolide, and Their Fluorinated Analogues. Journal of medicinal chemistry, 2015, 58, 7007-7020 |
| 1517410 | CIF | C15 H20 O3 | P 21 21 21 | 6.1945; 10.289; 21.907 90; 90; 90 | 1396.2 | Long, Jing; Zhang, Shan-Feng; Wang, Pan-Pan; Zhang, Xue-Mei; Yang, Zhong-Jin; Zhang, Quan; Chen, Yue Total syntheses of parthenolide and its analogues with macrocyclic stereocontrol. Journal of medicinal chemistry, 2014, 57, 7098-7112 |
| 1565895 | CIF | C15 H20 O4 | P 21 21 21 | 8.2975; 12.0102; 13.9497 90; 90; 90 | 1390.15 | Liu, Xingchen; Wang, Cheng; Li, Shang; Qu, Lailiang; Yin, Fucheng; Lu, Dehua; Luo, Heng; Chen, Xinye; Luo, Zhongwen; Cui, Ningjie; Wang, Xiaobing; Kong, Lingyi Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer. Journal of medicinal chemistry, 2021, 64, 17304-17325 |
| 1553268 | CIF | C15 H23 Cl Cu N6 O2 S | P 1 21/c 1 | 9.3959; 19.8889; 10.9744 90; 108.366; 90 | 1946.37 | Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of medicinal chemistry, 2019, 62, 512-530 |
| 1517409 | CIF | C15 H23 N O3 | P 21 21 21 | 11.012; 11.015; 12.183 90; 90; 90 | 1477.8 | Long, Jing; Zhang, Shan-Feng; Wang, Pan-Pan; Zhang, Xue-Mei; Yang, Zhong-Jin; Zhang, Quan; Chen, Yue Total syntheses of parthenolide and its analogues with macrocyclic stereocontrol. Journal of medicinal chemistry, 2014, 57, 7098-7112 |
| 1518235 | CIF | C15 H33 N O5 S | C 1 2 1 | 17.9092; 6.1043; 17.9815 90; 102.833; 90 | 1916.7 | Maolanon, Alex R.; Villadsen, Jesper S.; Christensen, Niels J.; Hoeck, Casper; Friis, Tina; Harris, Pernille; Gotfredsen, Charlotte H.; Fristrup, Peter; Olsen, Christian A. Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles. Journal of medicinal chemistry, 2014, 57, 9644-9657 |
| 1502668 | CIF | C16 H10 N3 | P 1 21/c 1 | 15.046; 9.845; 16.267 90; 98.773; 90 | 2381.4 | Tan, Caiping; Lai, Sensen; Wu, Shouhai; Hu, Sheng; Zhou, Lingjun; Chen, Yu; Wang, Minxu; Zhu, Yiping; Lian, Wu; Peng, Wenlie; Ji, Liangnian; Xu, Anlong Nuclear permeable ruthenium(II) β-carboline complexes induce autophagy to antagonize mitochondrial-mediated apoptosis. Journal of medicinal chemistry, 2010, 53, 7613-7624 |
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