Crystallography Open Database

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Searching journal of publication like 'Journal of Medicinal Chemistry'

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1506354 CIFC9 H8 I N O2P 1 21/c 14.1515; 16.0162; 14.1406
90; 97.411; 90
932.37Deng, Bo-Liang; Hartman, Tracy L.; Buckheit, Jr, Robert W; Pannecouque, Christophe; De Clercq, Erik; Fanwick, Phillip E.; Cushman, Mark
Synthesis, anti-HIV activity, and metabolic stability of new alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal of medicinal chemistry, 2005, 48, 6140-6155
1553278 CIFC9 H7 Cl N6P 21 21 215.436; 9.003; 21.664
90; 90; 90
1060.2Tokarenko, Anna; Lišková, Barbora; Smoleń, Sabina; Táborská, Natálie; Tichý, Michal; Gurská, Soňa; Perlíková, Pavla; Frydrych, Ivo; Tloušt'ová, Eva; Znojek, Pawel; Mertlíková-Kaiserová, Helena; Poštová Slavětínská, Lenka; Pohl, Radek; Klepetářová, Blanka; Khalid, Noor-Ul-Ain; Wenren, Yiqian; Laposa, Rebecca R.; Džubák, Petr; Hajdúch, Marián; Hocek, Michal
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
Journal of medicinal chemistry, 2018, 61, 9347-9359
1553279 CIFC9 H7 Cl N4P 1 21/n 18.2465; 6.6263; 16.392
90; 97.969; 90
887.07Tokarenko, Anna; Lišková, Barbora; Smoleń, Sabina; Táborská, Natálie; Tichý, Michal; Gurská, Soňa; Perlíková, Pavla; Frydrych, Ivo; Tloušt'ová, Eva; Znojek, Pawel; Mertlíková-Kaiserová, Helena; Poštová Slavětínská, Lenka; Pohl, Radek; Klepetářová, Blanka; Khalid, Noor-Ul-Ain; Wenren, Yiqian; Laposa, Rebecca R.; Džubák, Petr; Hajdúch, Marián; Hocek, Michal
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
Journal of medicinal chemistry, 2018, 61, 9347-9359
1505034 CIFC9 H17 N O4P 1 21 17.1718; 6.9079; 10.864
90; 107.338; 90
513.77Vyavahare, Vinod P.; Chakraborty, Chaitali; Maity, Biswanath; Chattopadhyay, Subrata; Puranik, Vedavati G.; Dhavale, Dilip D.
Synthesis of 1-deoxy-1-hydroxymethyl- and 1-deoxy-1-epi-hydroxymethyl castanospermine as new potential immunomodulating agents.
Journal of medicinal chemistry, 2007, 50, 5519-5523
1503670 CIFC9 H12 N4 SP -17.3747; 7.4532; 9.6324
97.192; 109.63; 95.02
489.97Kowol, Christian R.; Trondl, Robert; Heffeter, Petra; Arion, Vladimir B.; Jakupec, Michael A.; Roller, Alexander; Galanski, Markus; Berger, Walter; Keppler, Bernhard K.
Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.
Journal of medicinal chemistry, 2009, 52, 5032-5043
1507656 CIFC9 H11 N O SeP 1 21/n 19.598; 8.166; 12.75
90; 103.19; 90
972.9Gutiérrez-Hernández, Alejandro I; López-Cortés, José G; Ortega-Alfaro, M Carmen; Ramírez-Apan, M Teresa; Cázares-Marinero, José de Jesús; Toscano, Rubén A
Ferrocenylselenoamides: synthesis, characterization and cytotoxic properties.
Journal of medicinal chemistry, 2012, 55, 4652-4663
1505018 CIFC9 H11 Cl2 Cu N5 SP -18.649; 9.313; 9.371
68.69; 71.86; 79.27
666Tardito, Saverio; Bussolati, Ovidio; Maffini, Monica; Tegoni, Matteo; Giannetto, Marco; Dall'asta, Valeria; Franchi-Gazzola, Renata; Lanfranchi, Maurizio; Pellinghelli, Maria Angela; Mucchino, Claudio; Mori, Giovanni; Marchio, Luciano
Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells.
Journal of medicinal chemistry, 2007, 50, 1916-1924
1503672 CIFC7 H9 N5 SP n a 2118.5732; 5.5273; 17.2799
90; 90; 90
1773.95Kowol, Christian R.; Trondl, Robert; Heffeter, Petra; Arion, Vladimir B.; Jakupec, Michael A.; Roller, Alexander; Galanski, Markus; Berger, Walter; Keppler, Bernhard K.
Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.
Journal of medicinal chemistry, 2009, 52, 5032-5043
1508520 CIFC7 H17 Cl2 F3 N2 O4 PtP -16.1836; 8.0658; 15.5374
102.217; 92.75; 108.655
711.98Pichler, Verena; Heffeter, Petra; Valiahdi, Seied M.; Kowol, Christian R.; Egger, Alexander; Berger, Walter; Jakupec, Michael A.; Galanski, Markus; Keppler, Bernhard K.
Unsymmetric Mono- and Dinuclear Platinum(IV) Complexes Featuring an Ethylene Glycol Moiety: Synthesis, Characterization, and Biological Activity.
Journal of medicinal chemistry, 2012, 55, 11052-11061
1505024 CIFC68 H58 B Cl N4 RuP 1 21/c 110.6994; 29.8522; 18.8571
90; 116.835; 90
5374.4Vock, Carsten A.; Ang, Wee Han; Scolaro, Claudine; Phillips, Andrew D.; Lagopoulos, Lucienne; Juillerat-Jeanneret, Lucienne; Sava, Gianni; Scopelliti, Rosario; Dyson, Paul J.
Development of ruthenium antitumor drugs that overcome multidrug resistance mechanisms.
Journal of medicinal chemistry, 2007, 50, 2166-2175
1562742 CIFC68 H100 F4 N6 O21 S4C 1 2 132.412; 6.476; 23.549
90; 132.313; 90
3655Zhang, Dongfeng; Li, Peng; Gao, Yongxin; Song, Yaoyao; Zhu, Yaqin; Su, Hong; Yang, Beibei; Li, Li; Li, Gang; Gong, Ningbo; Lu, Yang; Shao, Huanjie; Yu, Chunrong; Huang, Haihong
Discovery of a Candidate Containing an (S)-3,3-Difluoro-1-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-inden Scaffold as a Highly Potent Pan-Inhibitor of the BCR-ABL Kinase Including the T315I-Resistant Mutant for the Treatment of Chronic Myeloid Leukemia
Journal of Medicinal Chemistry, 2021
1566547 CIFC60 H63 Br2 Cl N14 Ni O4P -19.7632; 15.6735; 19.622
87.172; 75.925; 85.319
2901.4Wittmann, Christopher; Bacher, Felix; Enyedy, Eva A.; Dömötör, Orsolya; Spengler, Gabriella; Madejski, Christian; Reynisson, Jóhannes; Arion, Vladimir B.
Highly Antiproliferative Latonduine and Indolo[2,3-<i>c</i>]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile.
Journal of medicinal chemistry, 2022, 65, 2238-2261
1506359 CIFC57 H58 N2 O22P 3115.6681; 15.6681; 17.4559
90; 90; 120
3711.12Post, Glen C.; Barthel, Benjamin L.; Burkhart, David J.; Hagadorn, John R.; Koch, Tad H.
Doxazolidine, a proposed active metabolite of doxorubicin that cross-links DNA.
Journal of medicinal chemistry, 2005, 48, 7648-7657
1503675 CIFC52 H65 N4 O26.5 S4P -113.699; 13.796; 15.189
88.402; 77.838; 81.671
2776.6Wang, Kui; Guo, Dong-Sheng; Zhang, Hong-Qing; Li, Dong; Zheng, Xi-Long; Liu, Yu
Highly effective binding of viologens by p-sulfonatocalixarenes for the treatment of viologen poisoning.
Journal of medicinal chemistry, 2009, 52, 6402-6412
1553276 CIFC49.75 H73 Cl3 Cu3 N15 O7.75 S3P 1 21/n 122.2413; 8.3324; 31.9121
90; 90.5654; 90
5913.8Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B.
New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action.
Journal of medicinal chemistry, 2019, 62, 512-530
1508917 CIFC49 H54 Cl2 Cu2 N12 S4P 1 21/c 115.1825; 11.7338; 29.6982
90; 100.534; 90
5201.5Palanimuthu, Duraippandi; Shinde, Sridevi Vijay; Somasundaram, Kumaravel; Samuelson, Ashoka G.
In Vitro and in Vivo Anticancer Activity of Copper Bis(thiosemicarbazone) Complexes.
Journal of medicinal chemistry, 2013, 56, 722-734
1553273 CIFC48.75 H69 Cl3 Cu3 N15 O3.75 S3P 1 21/n 124.702; 9.1959; 25.064
90; 100.971; 90
5589.4Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B.
New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action.
Journal of medicinal chemistry, 2019, 62, 512-530
1502661 CIFC48 H50 N16 Ni O11P -113.8735; 14.2569; 15.0005
106.463; 99.654; 113.031
2484.7Maldonado, Carmen R.; Marín, Clotilde; Olmo, Francisco; Huertas, Oscar; Quirós, Miguel; Sánchez-Moreno, Manuel; Rosales, María J; Salas, Juan M.
In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi.
Journal of medicinal chemistry, 2010, 53, 6964-6972
1503674 CIFC48 H44.5 N4 O20.25 S8P 1 21/n 112.6727; 30.0947; 13.5037
90; 96.832; 90
5113.5Wang, Kui; Guo, Dong-Sheng; Zhang, Hong-Qing; Li, Dong; Zheng, Xi-Long; Liu, Yu
Highly effective binding of viologens by p-sulfonatocalixarenes for the treatment of viologen poisoning.
Journal of medicinal chemistry, 2009, 52, 6402-6412
1501661 CIFC46 H36 Br4 N2 O7P 21 21 218.6598; 21.3183; 23.6397
90; 90; 90
4364.2Magedov, Igor V.; Frolova, Liliya; Manpadi, Madhuri; Bhoga, Uma devi; Tang, Hong; Evdokimov, Nikolai M.; George, Olivia; Georgiou, Kathy Hadje; Renner, Steffen; Getlik, Matthäus; Kinnibrugh, Tiffany L.; Fernandes, Manuel A.; Van slambrouck, Severine; Steelant, Wim F. A.; Shuster, Charles B.; Rogelj, Snezna; van Otterlo, Willem A. L.; Kornienko, Alexander
Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis.
Journal of medicinal chemistry, 2011, 54, 4234-4246

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