Crystallography Open Database
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Result: there are 271 entries in the selection
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Searching journal of publication like 'Journal of Medicinal Chemistry'
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1506354 | CIF | C9 H8 I N O2 | P 1 21/c 1 | 4.1515; 16.0162; 14.1406 90; 97.411; 90 | 932.37 | Deng, Bo-Liang; Hartman, Tracy L.; Buckheit, Jr, Robert W; Pannecouque, Christophe; De Clercq, Erik; Fanwick, Phillip E.; Cushman, Mark Synthesis, anti-HIV activity, and metabolic stability of new alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors. Journal of medicinal chemistry, 2005, 48, 6140-6155 |
1553278 | CIF | C9 H7 Cl N6 | P 21 21 21 | 5.436; 9.003; 21.664 90; 90; 90 | 1060.2 | Tokarenko, Anna; Lišková, Barbora; Smoleń, Sabina; Táborská, Natálie; Tichý, Michal; Gurská, Soňa; Perlíková, Pavla; Frydrych, Ivo; Tloušt'ová, Eva; Znojek, Pawel; Mertlíková-Kaiserová, Helena; Poštová Slavětínská, Lenka; Pohl, Radek; Klepetářová, Blanka; Khalid, Noor-Ul-Ain; Wenren, Yiqian; Laposa, Rebecca R.; Džubák, Petr; Hajdúch, Marián; Hocek, Michal Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides. Journal of medicinal chemistry, 2018, 61, 9347-9359 |
1553279 | CIF | C9 H7 Cl N4 | P 1 21/n 1 | 8.2465; 6.6263; 16.392 90; 97.969; 90 | 887.07 | Tokarenko, Anna; Lišková, Barbora; Smoleń, Sabina; Táborská, Natálie; Tichý, Michal; Gurská, Soňa; Perlíková, Pavla; Frydrych, Ivo; Tloušt'ová, Eva; Znojek, Pawel; Mertlíková-Kaiserová, Helena; Poštová Slavětínská, Lenka; Pohl, Radek; Klepetářová, Blanka; Khalid, Noor-Ul-Ain; Wenren, Yiqian; Laposa, Rebecca R.; Džubák, Petr; Hajdúch, Marián; Hocek, Michal Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides. Journal of medicinal chemistry, 2018, 61, 9347-9359 |
1505034 | CIF | C9 H17 N O4 | P 1 21 1 | 7.1718; 6.9079; 10.864 90; 107.338; 90 | 513.77 | Vyavahare, Vinod P.; Chakraborty, Chaitali; Maity, Biswanath; Chattopadhyay, Subrata; Puranik, Vedavati G.; Dhavale, Dilip D. Synthesis of 1-deoxy-1-hydroxymethyl- and 1-deoxy-1-epi-hydroxymethyl castanospermine as new potential immunomodulating agents. Journal of medicinal chemistry, 2007, 50, 5519-5523 |
1503670 | CIF | C9 H12 N4 S | P -1 | 7.3747; 7.4532; 9.6324 97.192; 109.63; 95.02 | 489.97 | Kowol, Christian R.; Trondl, Robert; Heffeter, Petra; Arion, Vladimir B.; Jakupec, Michael A.; Roller, Alexander; Galanski, Markus; Berger, Walter; Keppler, Bernhard K. Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation. Journal of medicinal chemistry, 2009, 52, 5032-5043 |
1507656 | CIF | C9 H11 N O Se | P 1 21/n 1 | 9.598; 8.166; 12.75 90; 103.19; 90 | 972.9 | Gutiérrez-Hernández, Alejandro I; López-Cortés, José G; Ortega-Alfaro, M Carmen; Ramírez-Apan, M Teresa; Cázares-Marinero, José de Jesús; Toscano, Rubén A Ferrocenylselenoamides: synthesis, characterization and cytotoxic properties. Journal of medicinal chemistry, 2012, 55, 4652-4663 |
1505018 | CIF | C9 H11 Cl2 Cu N5 S | P -1 | 8.649; 9.313; 9.371 68.69; 71.86; 79.27 | 666 | Tardito, Saverio; Bussolati, Ovidio; Maffini, Monica; Tegoni, Matteo; Giannetto, Marco; Dall'asta, Valeria; Franchi-Gazzola, Renata; Lanfranchi, Maurizio; Pellinghelli, Maria Angela; Mucchino, Claudio; Mori, Giovanni; Marchio, Luciano Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells. Journal of medicinal chemistry, 2007, 50, 1916-1924 |
1503672 | CIF | C7 H9 N5 S | P n a 21 | 18.5732; 5.5273; 17.2799 90; 90; 90 | 1773.95 | Kowol, Christian R.; Trondl, Robert; Heffeter, Petra; Arion, Vladimir B.; Jakupec, Michael A.; Roller, Alexander; Galanski, Markus; Berger, Walter; Keppler, Bernhard K. Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation. Journal of medicinal chemistry, 2009, 52, 5032-5043 |
1508520 | CIF | C7 H17 Cl2 F3 N2 O4 Pt | P -1 | 6.1836; 8.0658; 15.5374 102.217; 92.75; 108.655 | 711.98 | Pichler, Verena; Heffeter, Petra; Valiahdi, Seied M.; Kowol, Christian R.; Egger, Alexander; Berger, Walter; Jakupec, Michael A.; Galanski, Markus; Keppler, Bernhard K. Unsymmetric Mono- and Dinuclear Platinum(IV) Complexes Featuring an Ethylene Glycol Moiety: Synthesis, Characterization, and Biological Activity. Journal of medicinal chemistry, 2012, 55, 11052-11061 |
1505024 | CIF | C68 H58 B Cl N4 Ru | P 1 21/c 1 | 10.6994; 29.8522; 18.8571 90; 116.835; 90 | 5374.4 | Vock, Carsten A.; Ang, Wee Han; Scolaro, Claudine; Phillips, Andrew D.; Lagopoulos, Lucienne; Juillerat-Jeanneret, Lucienne; Sava, Gianni; Scopelliti, Rosario; Dyson, Paul J. Development of ruthenium antitumor drugs that overcome multidrug resistance mechanisms. Journal of medicinal chemistry, 2007, 50, 2166-2175 |
1562742 | CIF | C68 H100 F4 N6 O21 S4 | C 1 2 1 | 32.412; 6.476; 23.549 90; 132.313; 90 | 3655 | Zhang, Dongfeng; Li, Peng; Gao, Yongxin; Song, Yaoyao; Zhu, Yaqin; Su, Hong; Yang, Beibei; Li, Li; Li, Gang; Gong, Ningbo; Lu, Yang; Shao, Huanjie; Yu, Chunrong; Huang, Haihong Discovery of a Candidate Containing an (S)-3,3-Difluoro-1-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-inden Scaffold as a Highly Potent Pan-Inhibitor of the BCR-ABL Kinase Including the T315I-Resistant Mutant for the Treatment of Chronic Myeloid Leukemia Journal of Medicinal Chemistry, 2021 |
1566547 | CIF | C60 H63 Br2 Cl N14 Ni O4 | P -1 | 9.7632; 15.6735; 19.622 87.172; 75.925; 85.319 | 2901.4 | Wittmann, Christopher; Bacher, Felix; Enyedy, Eva A.; Dömötör, Orsolya; Spengler, Gabriella; Madejski, Christian; Reynisson, Jóhannes; Arion, Vladimir B. Highly Antiproliferative Latonduine and Indolo[2,3-<i>c</i>]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile. Journal of medicinal chemistry, 2022, 65, 2238-2261 |
1506359 | CIF | C57 H58 N2 O22 | P 31 | 15.6681; 15.6681; 17.4559 90; 90; 120 | 3711.12 | Post, Glen C.; Barthel, Benjamin L.; Burkhart, David J.; Hagadorn, John R.; Koch, Tad H. Doxazolidine, a proposed active metabolite of doxorubicin that cross-links DNA. Journal of medicinal chemistry, 2005, 48, 7648-7657 |
1503675 | CIF | C52 H65 N4 O26.5 S4 | P -1 | 13.699; 13.796; 15.189 88.402; 77.838; 81.671 | 2776.6 | Wang, Kui; Guo, Dong-Sheng; Zhang, Hong-Qing; Li, Dong; Zheng, Xi-Long; Liu, Yu Highly effective binding of viologens by p-sulfonatocalixarenes for the treatment of viologen poisoning. Journal of medicinal chemistry, 2009, 52, 6402-6412 |
1553276 | CIF | C49.75 H73 Cl3 Cu3 N15 O7.75 S3 | P 1 21/n 1 | 22.2413; 8.3324; 31.9121 90; 90.5654; 90 | 5913.8 | Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of medicinal chemistry, 2019, 62, 512-530 |
1508917 | CIF | C49 H54 Cl2 Cu2 N12 S4 | P 1 21/c 1 | 15.1825; 11.7338; 29.6982 90; 100.534; 90 | 5201.5 | Palanimuthu, Duraippandi; Shinde, Sridevi Vijay; Somasundaram, Kumaravel; Samuelson, Ashoka G. In Vitro and in Vivo Anticancer Activity of Copper Bis(thiosemicarbazone) Complexes. Journal of medicinal chemistry, 2013, 56, 722-734 |
1553273 | CIF | C48.75 H69 Cl3 Cu3 N15 O3.75 S3 | P 1 21/n 1 | 24.702; 9.1959; 25.064 90; 100.971; 90 | 5589.4 | Ohui, Kateryna; Afanasenko, Eleonora; Bacher, Felix; Ting, Rachel Lim Xue; Zafar, Ayesha; Blanco-Cabra, Núria; Torrents, Eduard; Dömötör, Orsolya; May, Nóra V; Darvasiova, Denisa; Enyedy, Éva A; Popović-Bijelić, Ana; Reynisson, Jóhannes; Rapta, Peter; Babak, Maria V.; Pastorin, Giorgia; Arion, Vladimir B. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of medicinal chemistry, 2019, 62, 512-530 |
1502661 | CIF | C48 H50 N16 Ni O11 | P -1 | 13.8735; 14.2569; 15.0005 106.463; 99.654; 113.031 | 2484.7 | Maldonado, Carmen R.; Marín, Clotilde; Olmo, Francisco; Huertas, Oscar; Quirós, Miguel; Sánchez-Moreno, Manuel; Rosales, María J; Salas, Juan M. In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi. Journal of medicinal chemistry, 2010, 53, 6964-6972 |
1503674 | CIF | C48 H44.5 N4 O20.25 S8 | P 1 21/n 1 | 12.6727; 30.0947; 13.5037 90; 96.832; 90 | 5113.5 | Wang, Kui; Guo, Dong-Sheng; Zhang, Hong-Qing; Li, Dong; Zheng, Xi-Long; Liu, Yu Highly effective binding of viologens by p-sulfonatocalixarenes for the treatment of viologen poisoning. Journal of medicinal chemistry, 2009, 52, 6402-6412 |
1501661 | CIF | C46 H36 Br4 N2 O7 | P 21 21 21 | 8.6598; 21.3183; 23.6397 90; 90; 90 | 4364.2 | Magedov, Igor V.; Frolova, Liliya; Manpadi, Madhuri; Bhoga, Uma devi; Tang, Hong; Evdokimov, Nikolai M.; George, Olivia; Georgiou, Kathy Hadje; Renner, Steffen; Getlik, Matthäus; Kinnibrugh, Tiffany L.; Fernandes, Manuel A.; Van slambrouck, Severine; Steelant, Wim F. A.; Shuster, Charles B.; Rogelj, Snezna; van Otterlo, Willem A. L.; Kornienko, Alexander Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis. Journal of medicinal chemistry, 2011, 54, 4234-4246 |
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