N-Protecting group tuning of the enantioselectivity in Strecker reactions of trifluoromethyl ketimines to synthesize quaternary α-trifluoromethyl amino nitriles by ion pair catalysis.
Authors of publication
Du, Mengyuan; Yu, Longhui; Du, Ting; Li, Zhaokun; Luo, Yueyang; Meng, Xiangyu; Tian, Zhengtao; Zheng, Changwu; Cao, Weiguo; Zhao, Gang
Journal of publication
Chemical communications (Cambridge, England)
Year of publication
2020
Journal volume
56
Journal issue
10
Pages of publication
1581 - 1584
a
9.2263 ± 0.0004 Å
b
15.7424 ± 0.0007 Å
c
11.8768 ± 0.0006 Å
α
90°
β
108.325 ± 0.002°
γ
90°
Cell volume
1637.56 ± 0.13 Å3
Cell temperature
193 ± 2 K
Ambient diffraction temperature
193 ± 2 K
Number of distinct elements
6
Space group number
14
Hermann-Mauguin space group symbol
P 1 21/n 1
Hall space group symbol
-P 2yn
Residual factor for all reflections
0.0389
Residual factor for significantly intense reflections
0.0291
Weighted residual factors for significantly intense reflections
0.0706
Weighted residual factors for all reflections included in the refinement
0.0753
Goodness-of-fit parameter for all reflections included in the refinement
