Information card for entry 7249817

Structure parameters

• Chemical name: ethyl 2-amino-4-(furan-2-yl)-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-3-carboxylate
• Formula: C19 H16 N2 O5
• Calculated formula: C19 H16 N2 O5
• Title of publication: Microwave-assisted synthesis and in vitro and in silico studies of pyrano[3,2-c]quinoline-3-carboxylates as dual acting anti-cancer and anti-microbial agents and potential topoisomerase II and DNA-gyrase inhibitors
• Authors of publication: Aly, Ashraf A.; Abd El-Naby, Hisham A.; Ahmed, Essam Kh.; Gedamy, Sageda A.; Rissanen, Kari; Nieger, Martin; Brown, Alan B.; Shehat, Michael G.; Shaaban, Marwa M.; Atta, Amal
• Journal of publication: RSC Advances
• Year of publication: 2025
• Journal volume: 15
• Journal issue: 3
• Pages of publication: 1941 - 1956
• a: 8.2266 ± 0.0002 Å
• b: 8.5847 ± 0.0003 Å
• c: 12.5866 ± 0.0003 Å
• α: 106.141 ± 0.003°
• β: 103.673 ± 0.002°
• γ: 100.32 ± 0.002°
• Cell volume: 800.6 ± 0.04 ų
• Cell temperature: 120 ± 2 K
• Ambient diffraction temperature: 120 ± 2 K
• Number of distinct elements: 4
• Space group number: 2
• Hermann-Mauguin space group symbol: P -1
• Hall space group symbol: -P 1
• Residual factor for all reflections: 0.0428
• Residual factor for significantly intense reflections: 0.0393
• Weighted residual factors for significantly intense reflections: 0.113
• Weighted residual factors for all reflections included in the refinement: 0.1155
• Goodness-of-fit parameter for all reflections included in the refinement: 1.066
• Diffraction radiation probe: x-ray
• Diffraction radiation wavelength: 1.54184 Å
• Diffraction radiation type: CuKα
• Has coordinates: Yes
• Has disorder: No
• Has Fobs: No