Information card for entry 7250184

Structure parameters

• Common name: Lenalidomide Dihydrate
• Chemical name: 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
• Formula: C13 H17 N3 O5
• Calculated formula: C13 H17 N3 O5
• Title of publication: Different thermal and solubility properties with an identical crystal structure – case of lenalidomide hydrate
• Authors of publication: Zhang, Qi; Zhu, Yitong; Xu, Yisheng; Yang, Huaiyu; Li, Wei; Zhang, Xiangyang
• Journal of publication: CrystEngComm
• Year of publication: 2025
• Journal volume: 27
• Journal issue: 18
• Pages of publication: 2815 - 2823
• a: 13.43 ± 0.0014 Å
• b: 8.8535 ± 0.001 Å
• c: 11.7594 ± 0.0012 Å
• α: 90°
• β: 99.231 ± 0.006°
• γ: 90°
• Cell volume: 1380.1 ± 0.3 ų
• Cell temperature: 281 ± 2 K
• Ambient diffraction temperature: 281.59 K
• Number of distinct elements: 4
• Space group number: 14
• Hermann-Mauguin space group symbol: P 1 21/c 1
• Hall space group symbol: -P 2ybc
• Residual factor for all reflections: 0.1059
• Residual factor for significantly intense reflections: 0.0806
• Weighted residual factors for significantly intense reflections: 0.2268
• Weighted residual factors for all reflections included in the refinement: 0.2677
• Goodness-of-fit parameter for all reflections included in the refinement: 1.063
• Diffraction radiation wavelength: 1.54178 Å
• Diffraction radiation type: CuKα
• Has coordinates: Yes
• Has disorder: No
• Has Fobs: No