Crystallography Open Database

Result : There are 17 entries in the selection

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Searching journal of publication like 'Journal of medicinal chemistry' volume of publication is 53

COD ID: 1502658
CIF file Formula: - C27 H23 Cl3 N4 O2 -
Comments: Yan, Lin; Huo, Pei; Debenham, John S.; Madsen-Duggan, Christina B; Lao, Julie; Chen, Richard Z.; Xiao, Jing Chen; Shen, Chun-Pyn; Stribling, D. Sloan; Shearman, Lauren P.; Strack, Alison M.; Tsou, Nancy; Ball, Richard G.; Wang, Junying; Tong, Xinchun; Bateman, Thomas J.; Reddy, Vijay B. G.; Fong, Tung M.; Hale, Jeffrey J. Discovery of N-[(4R)-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide (MK-5596) as a novel cannabinoid-1 receptor (CB1R) inverse agonist for the treatment of obesity. Journal of medicinal chemistry 53(10) (2010) 4028-4037
Space group: P 21 21 21
Cell volume: 2508.1
Cell parameters: 11.1695; 11.2252; 20.0044; 90; 90; 90;  

COD ID: 1502659
CIF file Formula: - C17 H18 N4 O2 S -
Comments: Ivachtchenko, Alexandre V.; Dmitriev, Dmitri E.; Golovina, Elena S.; Kadieva, Madina G.; Koryakova, Angela G.; Kysil, Volodymyr M.; Mitkin, Oleg D.; Okun, Ilya M.; Tkachenko, Sergey E.; Vorobiev, Anton A. (3-Phenylsulfonylcycloalkano[e and d]pyrazolo[1,5-a]pyrimidin-2-yl)amines: potent and selective antagonists of the serotonin 5-HT6 receptor. Journal of medicinal chemistry 53(14) (2010) 5186-5196
Space group: P -1
Cell volume: 779.2
Cell parameters: 8.187; 10.274; 11.169; 116.031; 92.445; 108.955;  

COD ID: 1502660
CIF file Formula: - C18 H20 N4 O2 S -
Comments: Ivachtchenko, Alexandre V.; Dmitriev, Dmitri E.; Golovina, Elena S.; Kadieva, Madina G.; Koryakova, Angela G.; Kysil, Volodymyr M.; Mitkin, Oleg D.; Okun, Ilya M.; Tkachenko, Sergey E.; Vorobiev, Anton A. (3-Phenylsulfonylcycloalkano[e and d]pyrazolo[1,5-a]pyrimidin-2-yl)amines: potent and selective antagonists of the serotonin 5-HT6 receptor. Journal of medicinal chemistry 53(14) (2010) 5186-5196
Space group: P 1 21/n 1
Cell volume: 1679.75
Cell parameters: 8.7051; 16.7415; 11.6695; 90; 98.996; 90;  

COD ID: 1502661
CIF file Formula: - C48 H50 N16 Ni O11 -
Comments: Maldonado, Carmen R.; Marín, Clotilde; Olmo, Francisco; Huertas, Oscar; Quirós, Miguel; Sánchez-Moreno, Manuel; Rosales, María J; Salas, Juan M. In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi. Journal of medicinal chemistry 53(19) (2010) 6964-6972
Space group: P -1
Cell volume: 2484.7
Cell parameters: 13.8735; 14.2569; 15.0005; 106.463; 99.654; 113.031;  

COD ID: 1502662
CIF file Formula: - C32 H28 N14 Ni O4 -
Comments: Maldonado, Carmen R.; Marín, Clotilde; Olmo, Francisco; Huertas, Oscar; Quirós, Miguel; Sánchez-Moreno, Manuel; Rosales, María J; Salas, Juan M. In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi. Journal of medicinal chemistry 53(19) (2010) 6964-6972
Space group: P -1
Cell volume: 1601.9
Cell parameters: 8.738; 12.35; 16.754; 73.779; 75.733; 69.31;  

COD ID: 1502663
CIF file Formula: - C36 H28 N14 Ni O4 -
Comments: Maldonado, Carmen R.; Marín, Clotilde; Olmo, Francisco; Huertas, Oscar; Quirós, Miguel; Sánchez-Moreno, Manuel; Rosales, María J; Salas, Juan M. In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi. Journal of medicinal chemistry 53(19) (2010) 6964-6972
Space group: C 1 2/c 1
Cell volume: 3451.9
Cell parameters: 13.226; 15.714; 16.609; 90; 90.107; 90;  

COD ID: 1502664
CIF file Formula: - C25 H52 Gd N5 O10 S -
Comments: Raghunand, Natarajan; Guntle, Gerald P.; Gokhale, Vijay; Nichol, Gary S.; Mash, Eugene A.; Jagadish, Bhumasamudram Design, synthesis, and evaluation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid derived, redox-sensitive contrast agents for magnetic resonance imaging. Journal of medicinal chemistry 53(18) (2010) 6747-6757
Space group: P -1
Cell volume: 1783.8
Cell parameters: 8.0364; 10.4906; 21.799; 76.573; 86.307; 88.816;  

COD ID: 1502665
CIF file Formula: - C16 H38 Cl2 N6 O2 Pt -
Comments: Marzano, Cristina; Mazzega Sbovata, Silvia; Gandin, Valentina; Colavito, Davide; Del Giudice, Elda; Michelin, Rino A.; Venzo, Alfonso; Seraglia, Roberta; Benetollo, Franco; Schiavon, Mariano; Bertani, Roberta A new class of antitumor trans-amine-amidine-Pt(II) cationic complexes: influence of chemical structure and solvent on in vitro and in vivo tumor cell proliferation. Journal of medicinal chemistry 53(16) (2010) 6210-6227
Space group: P -1
Cell volume: 605.3
Cell parameters: 7.336; 8.228; 10.622; 83.82; 103.76; 103.21;  

COD ID: 1502666
CIF file Formula: - C19 H28 B10 O -
Comments: Beer, Michael L.; Lemon, Jennifer; Valliant, John F. Preparation and evaluation of carborane analogues of tamoxifen. Journal of medicinal chemistry 53(22) (2010) 8012-8020
Space group: C 1 2 1
Cell volume: 2178.5
Cell parameters: 24.701; 6.5249; 18.081; 90; 131.621; 90;  

COD ID: 1502667
CIF file Formula: - C18 H26 B10 O -
Comments: Beer, Michael L.; Lemon, Jennifer; Valliant, John F. Preparation and evaluation of carborane analogues of tamoxifen. Journal of medicinal chemistry 53(22) (2010) 8012-8020
Space group: P 1 21/n 1
Cell volume: 2082.2
Cell parameters: 17.7571; 6.5335; 18.0351; 90; 95.656; 90;  

COD ID: 1502668
CIF file Formula: - C16 H10 N3 -
Comments: Tan, Caiping; Lai, Sensen; Wu, Shouhai; Hu, Sheng; Zhou, Lingjun; Chen, Yu; Wang, Minxu; Zhu, Yiping; Lian, Wu; Peng, Wenlie; Ji, Liangnian; Xu, Anlong Nuclear permeable ruthenium(II) β-carboline complexes induce autophagy to antagonize mitochondrial-mediated apoptosis. Journal of medicinal chemistry 53(21) (2010) 7613-7624
Space group: P 1 21/c 1
Cell volume: 2381.4
Cell parameters: 15.046; 9.845; 16.267; 90; 98.773; 90;  

COD ID: 1502669
CIF file Formula: - C37 H33 F12 N7 O2 P2 Ru -
Comments: Tan, Caiping; Lai, Sensen; Wu, Shouhai; Hu, Sheng; Zhou, Lingjun; Chen, Yu; Wang, Minxu; Zhu, Yiping; Lian, Wu; Peng, Wenlie; Ji, Liangnian; Xu, Anlong Nuclear permeable ruthenium(II) β-carboline complexes induce autophagy to antagonize mitochondrial-mediated apoptosis. Journal of medicinal chemistry 53(21) (2010) 7613-7624
Space group: P 1 21/c 1
Cell volume: 3850.4
Cell parameters: 14.756; 18.5156; 15.3421; 90; 113.283; 90;  

COD ID: 1502670
CIF file Formula: - C26.5 H33 N O6.5 -
Comments: Auzzas, Luciana; Larsson, Andreas; Matera, Riccardo; Baraldi, Annamaria; Deschênes-Simard, Benoît; Giannini, Giuseppe; Cabri, Walter; Battistuzzi, Gianfranco; Gallo, Grazia; Ciacci, Andrea; Vesci, Loredana; Pisano, Claudio; Hanessian, Stephen Non-natural macrocyclic inhibitors of histone deacetylases: design, synthesis, and activity. Journal of medicinal chemistry 53(23) (2010) 8387-8399
Space group: P 1 21 1
Cell volume: 2511.63
Cell parameters: 5.1805; 17.2642; 28.104; 90; 92.234; 90;  

COD ID: 1502671
CIF file Formula: - C22 H21 N3 O4 -
Comments: Zhu, Mingyan; Kim, Myung Hee; Lee, Sanghee; Bae, Su Jung; Kim, Seong Hwan; Park, Seung Bum Discovery of novel benzopyranyl tetracycles that act as inhibitors of osteoclastogenesis induced by receptor activator of NF-κB ligand. Journal of medicinal chemistry 53(24) (2010) 8760-8764
Space group: C 1 2/c 1
Cell volume: 3905.8
Cell parameters: 17.16; 8.241; 28.64; 90; 105.34; 90;  

COD ID: 1502672
CIF file Formula: - C33 H52 O3 -
Comments: Genet, Cédric; Strehle, Axelle; Schmidt, Céline; Boudjelal, Geoffrey; Lobstein, Annelise; Schoonjans, Kristina; Souchet, Michel; Auwerx, Johan; Saladin, Régis; Wagner, Alain Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes. Journal of medicinal chemistry 53(1) (2010) 178-190
Space group: P 21 21 21
Cell volume: 2901.94
Cell parameters: 7.2672; 11.8653; 33.6544; 90; 90; 90;  

COD ID: 1502673
CIF file Formula: - C19 H27 N4 O2.5 -
Comments: Vernekar, Sanjeev Kumar V.; Hallaq, Hasan Y.; Clarkson, Guy; Thompson, Andrew J.; Silvestri, Linda; Lummis, Sarah C. R.; Lochner, Martin Toward biophysical probes for the 5-HT3 receptor: structure-activity relationship study of granisetron derivatives. Journal of medicinal chemistry 53(5) (2010) 2324-2328
Space group: C 1 2/c 1
Cell volume: 7276.8
Cell parameters: 13.2127; 14.571; 37.9181; 90; 94.572; 90;  

COD ID: 1502674
CIF file Formula: - C19 H28 N4 O3 -
Comments: Vernekar, Sanjeev Kumar V.; Hallaq, Hasan Y.; Clarkson, Guy; Thompson, Andrew J.; Silvestri, Linda; Lummis, Sarah C. R.; Lochner, Martin Toward biophysical probes for the 5-HT3 receptor: structure-activity relationship study of granisetron derivatives. Journal of medicinal chemistry 53(5) (2010) 2324-2328
Space group: P -1
Cell volume: 903.66
Cell parameters: 7.3381; 10.1087; 13.655; 74.375; 75.612; 70.157;  


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