Information card for entry 1557185
| Formula |
C25 H23 F4 N5 O5 |
| Calculated formula |
C25 H23 F4 N5 O5 |
| Title of publication |
Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors. |
| Authors of publication |
Yang, Yaxi; Zhang, Rukang; Li, Zhaojun; Mei, Lianghe; Wan, Shili; Ding, Hong; Chen, Zhifeng; Xing, Jing; Feng, Huijin; Han, Jie; Jiang, Hualiang; Zheng, Mingyue; Luo, Cheng; Zhou, Bing |
| Journal of publication |
Journal of medicinal chemistry |
| Year of publication |
2020 |
| a |
10.1492 ± 0.0004 Å |
| b |
10.1392 ± 0.0004 Å |
| c |
25.2626 ± 0.0011 Å |
| α |
96.515 ± 0.001° |
| β |
96.515 ± 0.001° |
| γ |
107.35° |
| Cell volume |
2435.42 ± 0.17 Å3 |
| Cell temperature |
173 K |
| Ambient diffraction temperature |
173 K |
| Number of distinct elements |
5 |
| Space group number |
1 |
| Hermann-Mauguin space group symbol |
P 1 |
| Hall space group symbol |
P 1 |
| Residual factor for all reflections |
0.0361 |
| Residual factor for significantly intense reflections |
0.0342 |
| Weighted residual factors for significantly intense reflections |
0.0853 |
| Weighted residual factors for all reflections included in the refinement |
0.0873 |
| Goodness-of-fit parameter for all reflections included in the refinement |
1.043 |
| Diffraction radiation wavelength |
1.54178 Å |
| Diffraction radiation type |
CuKα |
| Has coordinates |
Yes |
| Has disorder |
No |
| Has Fobs |
No |
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The link is:
https://www.crystallography.net/1557185.html
