Information card for entry 2019771

Structure parameters

• Common name: Trimethoprim‒glutarimide (1/1)
• Chemical name: 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine‒piperidine-2,6-dione (1/1)
• Formula: C19 H25 N5 O5
• Calculated formula: C19 H25 N5 O5
• Title of publication: Cocrystals of the antibiotic trimethoprim with glutarimide and 3,3-dimethylglutarimide held together by three hydrogen bonds
• Authors of publication: Ton, Quoc Cuong; Egert, Ernst
• Journal of publication: Acta Crystallographica Section C
• Year of publication: 2015
• Journal volume: 71
• Journal issue: 1
• a: 8.774 ± 0.002 Å
• b: 17.046 ± 0.003 Å
• c: 14.168 ± 0.003 Å
• α: 90°
• β: 102.04 ± 0.03°
• γ: 90°
• Cell volume: 2072.4 ± 0.8 ų
• Cell temperature: 173 ± 2 K
• Ambient diffraction temperature: 173 ± 2 K
• Number of distinct elements: 4
• Space group number: 14
• Hermann-Mauguin space group symbol: P 1 21/n 1
• Hall space group symbol: -P 2yn
• Residual factor for all reflections: 0.0552
• Residual factor for significantly intense reflections: 0.0411
• Weighted residual factors for significantly intense reflections: 0.0995
• Weighted residual factors for all reflections included in the refinement: 0.1044
• Goodness-of-fit parameter for all reflections included in the refinement: 1.184
• Diffraction radiation wavelength: 0.71073 Å
• Diffraction radiation type: MoKα
• Has coordinates: Yes
• Has disorder: Yes
• Has Fobs: Yes