Information card for entry 4502144

Structure parameters

• Common name: amlodipine besylate dihydrate
• Formula: C26 H35 Cl N2 O10 S
• Calculated formula: C26 H35 Cl N2 O10 S
• SMILES: N1C(=C(C(C(=C1C)C(=O)OC)c1c(cccc1)Cl)C(=O)OCC)COCC[NH3+].S(=O)(=O)([O-])c1ccccc1.O.O
• Title of publication: Solid Forms of Amlodipine Besylate: Physicochemical, Structural, and Thermodynamic Characterization
• Authors of publication: Koradia, Vishal; Lopez de Diego, Heidi; Frydenvang, Karla; Ringkjøbing-Elema, Michiel; Müllertz, Anette; Bond, Andrew D.; Rantanen, Jukka
• Journal of publication: Crystal Growth & Design
• Year of publication: 2010
• Journal volume: 10
• Journal issue: 12
• Pages of publication: 5279
• a: 18.892 ± 0.002 Å
• b: 9.507 ± 0.0006 Å
• c: 16.357 ± 0.003 Å
• α: 90°
• β: 105.285 ± 0.012°
• γ: 90°
• Cell volume: 2833.9 ± 0.6 ų
• Cell temperature: 122 ± 1 K
• Ambient diffraction temperature: 122 ± 1 K
• Number of distinct elements: 6
• Space group number: 14
• Hermann-Mauguin space group symbol: P 1 21/c 1
• Hall space group symbol: -P 2ybc
• Residual factor for all reflections: 0.0528
• Residual factor for significantly intense reflections: 0.0327
• Weighted residual factors for significantly intense reflections: 0.0822
• Weighted residual factors for all reflections included in the refinement: 0.0894
• Goodness-of-fit parameter for all reflections included in the refinement: 1.031
• Diffraction radiation wavelength: 0.71073 Å
• Diffraction radiation type: MoKα
• Has coordinates: Yes
• Has disorder: No
• Has Fobs: No