Information card for entry 7121720

Structure parameters

• Formula: C25 H19 N3 O2
• Calculated formula: C25 H19 N3 O2
• Title of publication: Discovery of novel picolinamide-based derivatives as novel VEGFR-2 kinase inhibitors: synthesis, <i>in vitro</i> biological evaluation and molecular docking.
• Authors of publication: Sun, Wuji; Fang, Shubiao; Yan, Hong
• Journal of publication: MedChemComm
• Year of publication: 2018
• Journal volume: 9
• Journal issue: 6
• Pages of publication: 1054 - 1058
• a: 5.4568 ± 0.0007 Å
• b: 7.5939 ± 0.0005 Å
• c: 45.622 ± 0.003 Å
• α: 90°
• β: 90°
• γ: 90°
• Cell volume: 1890.5 ± 0.3 ų
• Cell temperature: 113 ± 2 K
• Ambient diffraction temperature: 113 ± 2 K
• Number of distinct elements: 4
• Space group number: 19
• Hermann-Mauguin space group symbol: P 21 21 21
• Hall space group symbol: P 2ac 2ab
• Residual factor for all reflections: 0.0303
• Residual factor for significantly intense reflections: 0.0298
• Weighted residual factors for significantly intense reflections: 0.0739
• Weighted residual factors for all reflections included in the refinement: 0.0743
• Goodness-of-fit parameter for all reflections included in the refinement: 1.079
• Diffraction radiation wavelength: 0.71073 Å
• Diffraction radiation type: MoKα
• Has coordinates: Yes
• Has disorder: No
• Has Fobs: No