Information card for entry 7250010

Structure parameters

• Formula: C23 H27 F2 N3 O2
• Calculated formula: C23 H27 F2 N3 O2
• Title of publication: Design, synthesis of 2-phenyl-1H-benzo[d]imidazole derivatives as 17β-HSD10 inhibitor for the treatment of Alzheimer's Disease
• Authors of publication: liu, Xiaohan; zhou, bin; Chen, Yan; lin, Jinyuan; shao, Chenwen; Chen, Liuzeng; Ruan, Banfeng; zhang, xingxing; Qian, Yong
• Journal of publication: RSC Medicinal Chemistry
• Year of publication: 2025
• a: 7.1699 ± 0.0013 Å
• b: 10.43 ± 0.002 Å
• c: 15.039 ± 0.003 Å
• α: 80.809 ± 0.008°
• β: 89.29 ± 0.007°
• γ: 78.757 ± 0.008°
• Cell volume: 1088.7 ± 0.4 ų
• Cell temperature: 223 K
• Ambient diffraction temperature: 223 K
• Number of distinct elements: 5
• Space group number: 2
• Hermann-Mauguin space group symbol: P -1
• Hall space group symbol: -P 1
• Residual factor for all reflections: 0.0711
• Residual factor for significantly intense reflections: 0.0479
• Weighted residual factors for significantly intense reflections: 0.1155
• Weighted residual factors for all reflections included in the refinement: 0.1373
• Goodness-of-fit parameter for all reflections included in the refinement: 1.035
• Diffraction radiation wavelength: 0.71073 Å
• Diffraction radiation type: MoKα
• Has coordinates: Yes
• Has disorder: No
• Has Fobs: No