Information card for entry 7250011

Structure parameters

• Formula: C16 H15 N3 O2
• Calculated formula: C16 H15 N3 O2
• Title of publication: Design, synthesis of 2-phenyl-1H-benzo[d]imidazole derivatives as 17β-HSD10 inhibitor for the treatment of Alzheimer's Disease
• Authors of publication: liu, Xiaohan; zhou, bin; Chen, Yan; lin, Jinyuan; shao, Chenwen; Chen, Liuzeng; Ruan, Banfeng; zhang, xingxing; Qian, Yong
• Journal of publication: RSC Medicinal Chemistry
• Year of publication: 2025
• a: 7.1923 ± 0.0007 Å
• b: 12.7507 ± 0.0011 Å
• c: 15.16 ± 0.0014 Å
• α: 90°
• β: 90°
• γ: 90°
• Cell volume: 1390.3 ± 0.2 ų
• Cell temperature: 223 K
• Ambient diffraction temperature: 223 K
• Number of distinct elements: 4
• Space group number: 19
• Hermann-Mauguin space group symbol: P 21 21 21
• Hall space group symbol: P 2ac 2ab
• Residual factor for all reflections: 0.0365
• Residual factor for significantly intense reflections: 0.0325
• Weighted residual factors for significantly intense reflections: 0.0813
• Weighted residual factors for all reflections included in the refinement: 0.0842
• Goodness-of-fit parameter for all reflections included in the refinement: 1.059
• Diffraction radiation wavelength: 1.54178 Å
• Diffraction radiation type: CuKα
• Has coordinates: Yes
• Has disorder: No
• Has Fobs: No