Organocatalytic enantioselective synthesis of 2,5,5-trisubstituted piperidines bearing a quaternary stereocenter. Vinyl sulfonamide as a new amine protecting group.
Authors of publication
Escolano, Marcos; Guerola, Marta; Torres, Javier; Gaviña, Daniel; Alzuet-Piña, Gloria; Sánchez-Rosello, María; Del Pozo, Carlos
Journal of publication
Chemical communications (Cambridge, England)
Year of publication
2020
Journal volume
56
Journal issue
9
Pages of publication
1425 - 1428
a
7.25874 ± 0.00008 Å
b
6.61591 ± 0.00006 Å
c
18.72215 ± 0.00018 Å
α
90°
β
91.4852 ± 0.0009°
γ
90°
Cell volume
898.795 ± 0.015 Å3
Cell temperature
149.99 ± 0.1 K
Ambient diffraction temperature
149.99 ± 0.1 K
Number of distinct elements
5
Space group number
4
Hermann-Mauguin space group symbol
P 1 21 1
Hall space group symbol
P 2yb
Residual factor for all reflections
0.0251
Residual factor for significantly intense reflections
0.0248
Weighted residual factors for significantly intense reflections
0.0655
Weighted residual factors for all reflections included in the refinement
0.0657
Goodness-of-fit parameter for all reflections included in the refinement
