Information card for entry 7249775

Structure parameters

• Formula: C35 H29 F N4 O8 S
• Calculated formula: C35 H29 F N4 O8 S
• Title of publication: Salt formation of cabozantinib with hydrochloric and hydrobromic acids – influence on the in vitro dissolution behavior and food effect
• Authors of publication: Ramesh, Sreela; Zmeškalová, Eliška; Kučeráková, Monika; Zvoníček, Vít; Šoóš, Miroslav
• Journal of publication: CrystEngComm
• Year of publication: 2025
• Journal volume: 27
• Journal issue: 7
• Pages of publication: 1026 - 1033
• a: 8.4541 ± 0.0001 Å
• b: 18.1835 ± 0.0004 Å
• c: 41.4054 ± 0.0006 Å
• α: 90°
• β: 90°
• γ: 90°
• Cell volume: 6365.05 ± 0.18 ų
• Cell temperature: 140 K
• Ambient diffraction temperature: 140 K
• Number of distinct elements: 6
• Space group number: 61
• Hermann-Mauguin space group symbol: P b c a
• Hall space group symbol: -P 2ac 2ab
• Residual factor for all reflections: 0.0431
• Residual factor for significantly intense reflections: 0.0376
• Weighted residual factors for all reflections: 0.0985
• Weighted residual factors for significantly intense reflections: 0.0945
• Weighted residual factors for all reflections included in the refinement: 0.0985
• Goodness-of-fit parameter for all reflections included in the refinement: 1.0167
• Diffraction radiation wavelength: 1.54184 Å
• Diffraction radiation type: CuKα
• Has coordinates: Yes
• Has disorder: No
• Has Fobs: No