Information card for entry 7249776

Structure parameters

• Formula: C28 H25 Cl F N3 O5
• Calculated formula: C28 H25 Cl F N3 O5
• Title of publication: Salt formation of cabozantinib with hydrochloric and hydrobromic acids – influence on the in vitro dissolution behavior and food effect
• Authors of publication: Ramesh, Sreela; Zmeškalová, Eliška; Kučeráková, Monika; Zvoníček, Vít; Šoóš, Miroslav
• Journal of publication: CrystEngComm
• Year of publication: 2025
• Journal volume: 27
• Journal issue: 7
• Pages of publication: 1026 - 1033
• a: 8.2418 ± 0.0002 Å
• b: 15.0392 ± 0.0003 Å
• c: 19.989 ± 0.0004 Å
• α: 90°
• β: 91.61 ± 0.0018°
• γ: 90°
• Cell volume: 2476.66 ± 0.09 ų
• Cell temperature: 95 ± 0.2 K
• Ambient diffraction temperature: 95 K
• Number of distinct elements: 6
• Space group number: 14
• Hermann-Mauguin space group symbol: P 1 21/c 1
• Hall space group symbol: -P 2ybc
• Residual factor for all reflections: 0.0376
• Residual factor for significantly intense reflections: 0.033
• Weighted residual factors for significantly intense reflections: 0.0923
• Weighted residual factors for all reflections included in the refinement: 0.0951
• Goodness-of-fit parameter for significantly intense reflections: 1.7055
• Goodness-of-fit parameter for all reflections included in the refinement: 1.6408
• Diffraction radiation probe: x-ray
• Diffraction radiation wavelength: 1.54184 Å
• Diffraction radiation type: CuKα
• Has coordinates: Yes
• Has disorder: No
• Has Fobs: No